Comparison of the foveal avascular zone in unilateral amblyopic patients with the fellow eye by using optical coherence tomography angiography (oct-a)

Abstract

Objective: To compare Foveal avascular zone of unilateral amblyopia to that of the contralateral eye in the same pa-tients by quantifying the foveal avascular zone (FAZ) with Superficial Vascular Plexus (SVP) optical coherence tomogra-phy angiography (OCT-A).
Methodology: A retrospective review of patients diagnosed with anisometropic amblyopic was done from January 2021 to October 2022 at Department of Ophthalmology and Visual Sciences, Civil Hospital Karachi and SMBB Trauma Cen-tre. Foveal avascular zone (FAZ) diameter was measured at horizontal and vertical axis through OCT-A. Data was en-tered and tabulated using SPSS 26.
Results: A comparative analysis of 60 eyes of 30 patients was done. The proportion of males to females was calculated as 2:3. Age range was from 17 to 37 years. The average vertical and horizontal FAZ diameter of SVP in normal eyes was measured to be 616.40 and 616.10 microns, whereas in amblyopic eyes, it was 618.80 and 621.30 microns, re-spectively.
Conclusion: There was no significant difference in the measurements in the vertical and horizontal diameter of amblyop-ic eyes with that of the fellow eye of the same patient, when the data was analysed in our study (p>0.29 and p>0.111 respectively).

Keywords: Dentistry practice, Diagnostic Tomography, Optical Tomography, Optical Coherence, Vision Disorders, Fo-vea Centralis, Limbus Cornea.